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KMID : 0358319870280040541
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Korean Journal of Urology
1987 Volume.28 No. 4 p.541 ~ p.548
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Effect of Enoxacin(Flumark) in Urinary Tract Infection: clinical and antimicrobial susceptibility evaluation
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김영균/Kim YK
이은식/이성원/정기현/이안기/Lee ES/Lee SW/Chung KH/Lee AK
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Abstract
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Effect of Enoxacin (Flumark), an oral pyridone carboxylic acid, in the urinary tract infection was evaluated clinically and susceptibility of 292 strains of microorganism isolated from urine to the various antimicrobial agents was tested and compared. Thirty six patients with urinary tract infection were given with 300 to 600mg of Enoxacin daily for 7 to 14 days according to severity of urinary tract infection. The clinical symptoms and urinary findings improved in 30 patients (83.3%) and no clinical response was achieved in 6 patients (16.7%), but revealing 100% response in 9 patients of acute uncomplicated cystitis. In the antimicrobial susceptibility test, Enoxacin was much superior to aminoglycoside, especially against Pseudomonas aeruginosa. Serratia spp., Enterobacter spp. and other Pseudomonas spp.. Enoxacin is a very effective and safe antimicrobial agent in treatment of the urinary tract infection.
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